Development of low grain arsenic rice by the fungal arsenic methyltransferase via bio-volatilization

Students of CSIR – National Botanical Research Institute, Lucknow, Shikha Verma and Dr Pankaj Kumar Verma won the award for a Development of low grain arsenic rice by the fungal arsenic methyltransferase via bio-volatilization. They carried their project work under the guidance of Dr Debasis Chakrabarty.

Numerous studies have been extensively documented for the benefits of Continuous Subcutaneous Insulin Infusion (CSII) over Multiple Daily Injections (MDI) for insulin therapy in Type 1 Diabetes Mellitus (T1DM) patients. Despite such overwhelming evidence in support, the adoption of CSII is sparse, particularly in resource-constrained settings like India. Apart from the institutional factors, fixed and recurring costs of such a device are often found to be a withholding factor for widespread application. The abstract describes the development of a novel, affordable insulin pump for T1DM patients matching the specifications of a state-of-the-art pump, while significantly bringing down the fabrication cost. Most pumps rely on a lead screw/nut coupled with a geared DC motor to achieve precise micro-motion. These motors typically make use of micro-gears as a means of speed reduction, which is inherently expensive to manufacture. Consequently, they contribute significantly to the final cost of a pump. In this work, we take an innovative approach to distribute the requisite speed reduction in multiple stages, with an acceptable compromise on the product size. The system is actuated by a nominal DC geared motor and a novel mechanism of converting continuous rotary input to intermittent output. The kinematic chain is feedback-controlled which ensures volumetric accuracy of the delivered fluid. The pump can be wirelessly controlled via a remote. The same wireless channel can be used to connect to a Continuous Glucose Monitoring (CGM) device for subsequent integration with an Artificial Pancreas system. Preliminary accuracy tests showed promising results when compared with commercially available devices.

The Hon’ble Vice President of India, Shri M. Venkaiah Naidu awarded the Gandhian Young Technological Innovation (GYTI) Award to Shikha Verma and Dr Pankaj Kumar Verma, CSIR – National Botanical Research Institute, Lucknow at the GYTI 2019 Awards function held at Vigyan Bhawan, New Delhi on July 06, 2019.

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